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1

Cancer Diagnosis Using a Liquid Biopsy: Challenges and Expectations

Castro-Giner, Francesc, Gkountela, Sofia, Donato, Cinzia, Alborelli, Ilaria, Quagliata, Luca, Ng, Charlotte, Piscuoglio, Salvatore, Aceto, Nicola

Journal:

Year:

2018

Language:

english

File:

PDF, 270 KB

english, 2018

2

Circulating Tumor Cell Clustering Shapes DNA Methylation to Enable Metastasis Seeding

Gkountela, Sofia, Castro-Giner, Francesc, Szczerba, Barbara Maria, Vetter, Marcus, Landin, Julia, Scherrer, Ramona, Krol, Ilona, Scheidmann, Manuel C., Beisel, Christian, Stirnimann, Christian U., Kur

Journal:

Year:

2019

Language:

english

File:

PDF, 8.66 MB

english, 2019

3

A Polymorphic p53 Response Element in KIT Ligand Influences Cancer Risk and Has Undergone Natural Selection

Zeron-Medina, Jorge, Wang, Xuting, Repapi, Emmanouela, Campbell, Michelle R., Su, Dan, Castro-Giner, Francesc, Davies, Benjamin, Peterse, Elisabeth F.P., Sacilotto, Natalia, Walker, Graeme J., Terzian

Journal:

Year:

2013

Language:

english

File:

PDF, 2.98 MB

english, 2013

4

A pooling-based genome-wide analysis identifies new potential candidate genes for atopy in the European Community Respiratory Health Survey (ECRHS)

Francesc Castro-Giner, Mariona Bustamante, Juan Ramon González, Manolis Kogevinas, Deborah Jarvis, Joachim Heinrich, Josep-Maria Antó, Matthias Wjst, Xavier Estivill, Rafael de Cid

Journal:

BMC Medical Genetics

Year:

2009

Language:

english

File:

PDF, 1.12 MB

english, 2009

5

A screening methodology based on Random Forests to improve the detection of gene–gene interactions

De Lobel, Lizzy, Geurts, Pierre, Baele, Guy, Castro-Giner, Francesc, Kogevinas, Manolis, Van Steen, Kristel

Journal:

European Journal of Human Genetics

Year:

2010

Language:

english

File:

PDF, 357 KB

english, 2010

6

Spinal Muscular Atrophy Associated with Progressive Myoclonic Epilepsy Is Caused by Mutations in ASAH1

Jie Zhou, Marcel Tawk, Francesco Danilo Tiziano, Julien Veillet, Monica Bayes, Flora Nolent, Virginie Garcia, Serenella Servidei, Enrico Bertini, Francesc Castro-Giner, Yavuz Renda, Stéphane Carpentie

Journal:

The American Journal of Human Genetics

Year:

2012

Language:

english

File:

PDF, 791 KB

english, 2012

7

STAT4 gene polymorphism is associated with psoriasis in the genetically homogeneous population of Crete, Greece

Maria I. Zervou, George N. Goulielmos, Francesc Castro-Giner, Androniki D. Tosca, Sabine Krueger-Krasagakis

Journal:

Human Immunology

Year:

2009

Language:

english

File:

PDF, 245 KB

english, 2009

8

A CD40 and an NCOA5 gene polymorphism confer susceptibility to psoriasis in a Southern European population: A case–control study

Maria I. Zervou, George N. Goulielmos, Francesc Castro-Giner, Dimitrios T. Boumpas, Androniki D. Tosca, Sabine Krueger-Krasagakis

Journal:

Human Immunology

Year:

2011

Language:

english

File:

PDF, 286 KB

english, 2011

9

Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy

Balbás-Martínez, Cristina, Sagrera, Ana, Carrillo-de-Santa-Pau, Enrique, Earl, Julie, Márquez, Mirari, Vazquez, Miguel, Lapi, Eleonora, Castro-Giner, Francesc, Beltran, Sergi, Bayés, Mònica, Carrato,

Journal:

Nature Genetics

Year:

2013

Language:

english

File:

PDF, 986 KB

english, 2013

10

Influence of Glutathione S-Transferase Polymorphisms on Cognitive Functioning Effects Induced by p,p′-DDT among Preschoolers doi:10.1289/ehp.11303

Eva Morales, Jordi Sunyer, Francesc Castro-Giner, Xavier Estivill, Jordi Julvez, Nuria Ribas-Fitó, Maties Torrent, Joan O. Grimalt and Rafael de Cid

Journal:

Environmental Health Perspectives

Year:

2008

Language:

english

File:

PDF, 1.38 MB

english, 2008

11

Traffic-Related Air Pollution, Oxidative Stress Genes, and Asthma (ECHRS)

Francesc Castro-Giner, Nino Künzli, Bénédicte Jacquemin, Bertil Forsberg, Rafael de Cid, Jordi Sunyer, Deborah Jarvis, David Briggs, Danielle Vienneau, Dan Norback, Juan R. González, Stefano Guerra, C

Journal:

Environmental Health Perspectives

Year:

2009

Language:

english

File:

PDF, 1.19 MB

english, 2009

12

Education: Gene-Environment Interactions in Asthma

F. Castro-Giner, F. Kauffmann, R. de Cid and M. Kogevinas

Journal:

Occupational and Environmental Medicine

Year:

2006

Language:

english

File:

PDF, 3.65 MB

english, 2006

13

The Protein Tyrosine Phosphatase, Non-Receptor Type 22 R620W Polymorphism Does Not Confer Susceptibility to Psoriasis in the Genetic Homogeneous Population of Crete

Zervou, Maria I., Castro-Giner, Francesc, Sidiropoulos, Prodromos, Boumpas, Dimitrios T., Tosca, Androniki D., Krueger-Krasagakis, Sabine

Journal:

Genetic Testing and Molecular Biomarkers

Year:

2010

Language:

english

File:

PDF, 94 KB

english, 2010

14

Respiratory health and endotoxin: associations and modification by CD14/-260 genotype

Bakolis, I., Doekes, G., Heinrich, J., Zock, J. P., Heederik, D., Kogevinas, M., Guerra, S., Norback, D., Ramasamy, A., Nevalainen, A., Svanes, C., Chen, C. M., Verlato, G., Olivieri, M., Castro-Giner

Journal:

European Respiratory Journal

Year:

2012

Language:

english

File:

PDF, 438 KB

english, 2012

15

ADRB2 Gly16Arg polymorphism, asthma control and lung function decline

Rebordosa, C., Kogevinas, M., Guerra, S., Castro-Giner, F., Jarvis, D., Cazzoletti, L., Pin, I., Siroux, V., Wjst, M., Anto, J. M., de Marco, R., Estivill, X., Corsico, A. G., Nielsen, R., Janson, C.

Journal:

European Respiratory Journal

Year:

2011

Language:

english

File:

PDF, 305 KB

english, 2011

16

Recurrent chromosomal gains and heterogeneous driver mutations characterise papillary renal cancer evolution

Kovac, Michal, Navas, Carolina, Horswell, Stuart, Salm, Max, Bardella, Chiara, Rowan, Andrew, Stares, Mark, Castro-Giner, Francesc, Fisher, Rosalie, de Bruin, Elza C., Kovacova, Monika, Gorman, Maggie

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 1.12 MB

english, 2015

17

Joint effect of obesity and TNFA variability on asthma: two international cohort studies

Castro-Giner, F., Kogevinas, M., Imboden, M., de Cid, R., Jarvis, D., Machler, M., Berger, W., Burney, P., Franklin, K. A., Gonzalez, J. R., Heinrich, J., Janson, C., Omenaas, E., Pin, I., Rochat, T.,

Journal:

European Respiratory Journal

Year:

2009

Language:

english

File:

PDF, 381 KB

english, 2009

18

Positionally cloned genes and age-specific effects in asthma and atopy: an international population-based cohort study (ECRHS)

Castro-Giner, F., de Cid, R., Gonzalez, J. R., Jarvis, D., Heinrich, J., Janson, C., Omenaas, E. R., Matheson, M. C., Pin, I., Anto, J. M., Wjst, M., Estivill, X., Kogevinas, M.

Journal:

Year:

2010

Language:

english

File:

PDF, 368 KB

english, 2010

19

TNFA -308G>A in two international population-based cohorts and risk of asthma

Castro-Giner, F., Kogevinas, M., Machler, M., de Cid, R., Van Steen, K., Imboden, M., Schindler, C., Berger, W., Gonzalez, J. R., Franklin, K. A., Janson, C., Jarvis, D., Omenaas, E., Burney, P., Roch

Journal:

European Respiratory Journal

Year:

2008

Language:

english

File:

PDF, 391 KB

english, 2008

20

GSTM1 polymorphisms modify the effect of maternal smoking during pregnancy on cognitive functioning in preschoolers

Morales, E., Sunyer, J., Julvez, J., Castro-Giner, F., Estivill, X., Torrent, M., De Cid, R.

Journal:

International Journal of Epidemiology

Year:

2009

Language:

english

File:

PDF, 93 KB

english, 2009

21

Air pollution, oxidative stress and dietary supplementation: a review

Romieu, I., Castro-Giner, F., Kunzli, N., Sunyer, J.

Journal:

European Respiratory Journal

Year:

2008

Language:

english

File:

PDF, 413 KB

english, 2008

22

Interaction between gas cooking and GSTM1 null genotype in bronchial responsiveness: results from the European Community Respiratory Health Survey

Amaral, A. F. S., Ramasamy, A., Castro-Giner, F., Minelli, C., Accordini, S., Sorheim, I.-C., Pin, I., Kogevinas, M., Jogi, R., Balding, D. J., Norback, D., Verlato, G., Olivieri, M., Probst-Hensch, N

Journal:

Year:

2014

Language:

english

File:

PDF, 1.36 MB

english, 2014

23

Traffic-Related Air Pollution, Oxidative Stress Genes, and Asthma (ECHRS)

Castro-Giner, Francesc, Künzli, Nino, Jacquemin, Bénédicte, Forsberg, Bertil, de Cid, Rafael, Sunyer, Jordi, Jarvis, Deborah, Briggs, David, Vienneau, Danielle, Norback, Dan, González, Juan R., Guerra

Journal:

Environmental Health Perspectives

Year:

2009

Language:

english

File:

PDF, 913 KB

english, 2009

24

Gene-environment interactions in asthma

Castro-Giner, F, Kauffmann, F, de Cid, R, Kogevinas, M

Journal:

Occupational and Environmental Medicine

Year:

2006

Language:

english

File:

PDF, 223 KB

english, 2006

25

Exome sequencing reveals AMER1 as a frequently mutated gene in colorectal cancer

Sanz-Pamplona, R., Lopez-Doriga, A., Pare-Brunet, L., Lazaro, K., Bellido, F., Alonso, M. H., Ausso, S., Guino, E., Beltran, S., Castro-Giner, F., Gut, M., Sanjuan, X., Closa, A., Cordero, D., Moron-D

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 922 KB

english, 2015

26

The mini-driver model of polygenic cancer evolution

F. Castro-giner, P. Ratcliffe, I. Tomlinson

Year:

2015

Language:

english

File:

PDF, 244 KB

english, 2015

27

Exome sequencing of osteosarcoma reveals mutation signatures reminiscent of BRCA deficiency

Kovac, Michal, Blattmann, Claudia, Ribi, Sebastian, Smida, Jan, Mueller, Nikola S., Engert, Florian, Castro-Giner, Francesc, Weischenfeldt, Joachim, Kovacova, Monika, Krieg, Andreas, Andreou, Dimosthe

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 1.14 MB

english, 2015

28

The importance of p53 pathway genetics in inherited and somatic cancer genomes

Stracquadanio, Giovanni, Wang, Xuting, Wallace, Marsha D., Grawenda, Anna M., Zhang, Ping, Hewitt, Juliet, Zeron-Medina, Jorge, Castro-Giner, Francesc, Tomlinson, Ian P., Goding, Colin R., Cygan, Kami

Journal:

Nature Reviews Cancer

Year:

2016

File:

PDF, 875 KB

2016

29

The importance of p53 pathway genetics in inherited and somatic cancer genomes

Stracquadanio, Giovanni, Wang, Xuting, Wallace, Marsha D., Grawenda, Anna M., Zhang, Ping, Hewitt, Juliet, Zeron-Medina, Jorge, Castro-Giner, Francesc, Tomlinson, Ian P., Goding, Colin R., Cygan, Kami

Journal:

Nature Reviews Cancer

Year:

2016

Language:

english

File:

PDF, 875 KB

english, 2016

30

Polymorphisms in the p53 pathway are enriched in cancer susceptibility loci and share characteristics with somatic pathway mutations

Stracquadanio, G., Wallace, M., Grawenda, A.M., Zhang, P., Hewitt, J., Zeron-Medina, J., Castro-Giner, F., Tomlinson, I.P., Goding, C.R., Cygan, K.J., Fairbrother, W.G., Thomas, L.F., Sætrom, P., Gemi

Journal:

European Journal of Cancer

Year:

2016

Language:

english

File:

PDF, 57 KB

english, 2016

31

Differential clonal evolution in oesophageal cancers in response to neo-adjuvant chemotherapy

Findlay, John M., Castro-Giner, Francesc, Makino, Seiko, Rayner, Emily, Kartsonaki, Christiana, Cross, William, Kovac, Michal, Ulahannan, Danny, Palles, Claire, Gillies, Richard S., MacGregor, Thomas

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 820 KB

english, 2016

32

Type 2 innate Lymphoid Cells Disrupt Bronchial Epithelial Barrier Integrity by Targeting Tight Junctions Via IL-13 in Asthma

Sugita, Kazunari, Steer, Catherine A., Martinez-Gonzalez, Itziar, Altunbulakli, Can, Morita, Hideaki, Castro-Giner, Francesc, Kubo, Terufumi, Wawrzyniak, Paulina, Rückert, Beate, Sudo, Katsuko, Nakae,

Journal:

Journal of Allergy and Clinical Immunology

Year:

2017

Language:

english

File:

PDF, 5.94 MB

english, 2017

33

Translational study identifies XPF and MUS81 as predictive biomarkers for oxaliplatin-based peri-operative chemotherapy in patients with esophageal adenocarcinoma

MacGregor, T. P., Carter, R., Gillies, R. S., Findlay, J. M., Kartsonaki, C., Castro-Giner, F., Sahgal, N., Wang, L. M., Chetty, R., Maynard, N. D., Cazier, J. B., Buffa, F., McHugh, P. J., Tomlinson,

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 1.34 MB

english, 2018

34

Lack of Association of Variants Previously Associated with Anti-TNF Medication Response in Rheumatoid Arthritis Patients: Results from a Homogeneous Greek Population

Zervou, Maria I., Myrthianou, Efsevia, Flouri, Irene, Plant, Darren, Chlouverakis, Gregory, Castro-Giner, Francesc, Rapsomaniki, Panayiota, Barton, Anne, Boumpas, Dimitrios T., Sidiropoulos, Prodromos

Journal:

Year:

2013

Language:

english

File:

PDF, 229 KB

english, 2013

35

Beyond Enumeration: Functional and Computational Analysis of Circulating Tumor Cells to Investigate Cancer Metastasis

Castro-Giner, Francesc, Scheidmann, Manuel C., Aceto, Nicola

Journal:

Frontiers in Medicine

Year:

2018

Language:

english

File:

PDF, 204 KB

english, 2018

36

Pain-Associated Transcriptome Changes in Synovium of Knee Osteoarthritis Patients

Bratus-Neuenschwander, Anna, Castro-Giner, Francesc, Frank-Bertoncelj, Mojca, Aluri, Sirisha, Fucentese, Sandro, Schlapbach, Ralph, Sprott, Haiko

Journal:

Year:

2018

Language:

english

File:

PDF, 1.73 MB

english, 2018

37

Detection of circulating tumour cell clusters in human glioblastoma

Krol, Ilona, Castro-Giner, Francesc, Maurer, Martina, Gkountela, Sofia, Szczerba, Barbara Maria, Scherrer, Ramona, Coleman, Niamh, Carreira, Suzanne, Bachmann, Felix, Anderson, Stephanie, Engelhardt,

Journal:

British Journal of Cancer

Year:

2018

Language:

english

File:

PDF, 525 KB

english, 2018

38

Relations between epidermal barrier dysregulation and Staphylococcus species–dominated microbiome dysbiosis in patients with atopic dermatitis

Altunbulakli, Can, Reiger, Matthias, Neumann, Avidan U., Garzorz-Stark, Natalie, Fleming, Megan, Huelpuesch, Claudia, Castro-Giner, Francesc, Eyerich, Kilian, Akdis, Cezmi A., Traidl-Hoffmann, Claudia

Journal:

Journal of Allergy and Clinical Immunology

Year:

2018

Language:

english

File:

PDF, 3.57 MB

english, 2018

39

Denosumab treatment is associated with the absence of circulating tumor cells in patients with breast cancer

Vetter, Marcus, Landin, Julia, Szczerba, Barbara Maria, Castro-Giner, Francesc, Gkountela, Sofia, Donato, Cinzia, Krol, Ilona, Scherrer, Ramona, Balmelli, Catharina, Malinovska, Alexandra, Zippelius,

Journal:

Breast Cancer Research

Year:

2018

Language:

english

File:

PDF, 618 KB

english, 2018

40

Neutrophils escort circulating tumour cells to enable cell cycle progression

Szczerba, Barbara Maria, Castro-Giner, Francesc, Vetter, Marcus, Krol, Ilona, Gkountela, Sofia, Landin, Julia, Scheidmann, Manuel C., Donato, Cinzia, Scherrer, Ramona, Singer, Jochen, Beisel, Christia

Journal:

Year:

2019

File:

PDF, 9.92 MB

2019

41

Micromanipulation of Circulating Tumor Cells for Downstream Molecular Analysis and Metastatic Potential Assessment

Donato, Cinzia, Szczerba, Barbara M., Scheidmann, Manuel C., Castro-Giner, Francesc, Aceto, Nicola

Journal:

Journal of Visualized Experiments

Year:

2019

Language:

english

File:

PDF, 960 KB

english, 2019

42

High degree of polyclonality hinders somatic mutation calling in lung brush samples of COPD cases and controls

Thun, Gian-Andri, Derdak, Sophia, Castro-Giner, Francesc, Apunte-Ramos, Katherine, Águeda, Lidia, Wjst, Matthias, Boland, Anne, Deleuze, Jean-François, Kolsum, Umme, Heiss-Neumann, Marion S., Nowinski

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 1.29 MB

english, 2019

43

Skin barrier damage after exposure to para-phenylenediamine

Meisser, Sanne S., Altunbulakli, Can, Bandier, Josefine, Opstrup, Morten S., Castro-Giner, Francesc, Akdis, Mübeccel, Bonefeld, Charlotte M., Johansen, Jeanne D., Akdis, Cezmi A.

Journal:

Journal of Allergy and Clinical Immunology

Year:

2019

File:

PDF, 3.45 MB

2019

44

High degree of polyclonality hinders somatic mutation calling in lung brush samples of COPD cases and controls

Thun, Gian-Andri, Derdak, Sophia, Castro-Giner, Francesc, Apunte-Ramos, Katherine, Águeda, Lidia, Wjst, Matthias, Boland, Anne, Deleuze, Jean-François, Kolsum, Umme, Heiss-Neumann, Marion S., Nowinski

Journal:

Scientific Reports

Year:

2019

File:

PDF, 1.29 MB

2019

45

Tracking cancer progression: from circulating tumor cells to metastasis

Castro-Giner, Francesc, Aceto, Nicola

Journal:

Genome Medicine

Year:

2020

Language:

english

File:

PDF, 378 KB

english, 2020

46

A novel proangiogenic B cell subset is increased in cancer and chronic inflammation

van de Veen, Willem, Globinska, Anna, Jansen, Kirstin, Straumann, Alex, Kubo, Terufumi, Verschoor, DaniÃ«lle, Wirz, Oliver F., Castro-Giner, Francesc, Tan, Ge, RÃ¼ckert, Beate, Ochsner, Urs, Herrmann,

Journal:

Science Advances

Year:

2020

File:

PDF, 1.09 MB

2020

47

Hypoxia Triggers the Intravasation of Clustered Circulating Tumor Cells

Donato, Cinzia, Kunz, Leo, Castro-Giner, Francesc, Paasinen-Sohns, Aino, Strittmatter, Karin, Szczerba, Barbara Maria, Scherrer, Ramona, Di Maggio, Nunzia, Heusermann, Wolf, Biehlmaier, Oliver, Beisel

Journal:

Year:

2020

File:

PDF, 6.51 MB

2020

48

Circulating tumor cells: Ready for translation?

Diamantopoulou, Zoi, Castro-Giner, Francesc, Aceto, Nicola

Journal:

Journal of Experimental Medicine

Year:

2020

File:

PDF, 838 KB

2020